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Perspective23 Apr 2024 Threonine fuels brain tumor development through a conserved tRNA modification A CRISPR dropout display screen for tRNA regulators recognized YRDC as the top critical gene in glioblastoma stem cells.Avoidance trials are for those who would not have cancer but are at a substantial possibility for establishing cancer or for canc
Threonine functions as a substrate of YRDC to facilitate the N6-threonylcarbamoyladenosine (t6A) tRNA modification and shift translation towards mitosis-associated genes by using a codon bias. Our findings assistance concentrating on glioblastoma growth by a very well-tolerated dietary therapy.News & Views29 Mar 2024 KRAS degradation averts PDAC ch
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